Pesquisa de medicamentos por nome

Doxorubicin (Conventional) e Cardiomiopatia

Resultado da verificação da interação do medicamento Doxorubicin (Conventional) com doença Cardiomiopatia quanto a segurança no uso em conjunto.

Resultado da verificação:

Doxorubicin (Conventional) <> Cardiomiopatia

Relevância: 23.07.2019 Revisor: Shkutko P.M., M.D., in

Na verificação da interação, conforme informações das fontes confiáveis como Drugs.com, Rxlist.com, Webmd.com, Medscape.com, foram identificadas as contra-indicações ou efeitos colaterais que podem prejudicar a saúde ou aumentar efeito negativo ao consumir o medicamento com esta doença concomitante.

Consumidor:

Dano miocárdico, incluindo aguda a insuficiência ventricular esquerda pode ocorrer com a doxorrubicina. O risco de cardiomiopatia é proporcional à exposição cumulativa com taxas de incidência de 1% a 20% para o acumulado de doses variando de 300 mg/m2 a 500 mg/m2 quando a doxorrubicina é administrado a cada 3 semanas. O risco de cardiomiopatia é ainda maior, com concomitante cardiotoxic terapia. Além disso, a doxorrubicina pode também causar arritmias, inclusive com risco de vida eventos em qualquer ponto durante o tratamento. Avaliar FEVE antes e regularmente durante e após o tratamento com doxorrubicina. A doxorrubicina é contra-indicado em pacientes com grave insuficiência miocárdica e recente de infarto do miocárdio (últimos 6 meses).

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