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Dorzolamide and Timolol Ophthalmic Solution e Disfunção renal

Resultado da verificação da interação do medicamento Dorzolamide and Timolol Ophthalmic Solution com doença Disfunção renal quanto a segurança no uso em conjunto.

Resultado da verificação:

Dorzolamide and Timolol Ophthalmic Solution <> Disfunção renal

Relevância: 23.07.2019 Revisor: Shkutko P.M., M.D., in

Na verificação da interação, conforme informações das fontes confiáveis como Drugs.com, Rxlist.com, Webmd.com, Medscape.com, foram identificadas as contra-indicações ou efeitos colaterais que podem prejudicar a saúde ou aumentar efeito negativo ao consumir o medicamento com esta doença concomitante.

Consumidor:

Sulfonamidas pode ser absorvido sistemicamente, quando aplicado à pele, olhos ou membranas mucosas. Uma vez absorvido, sulfonamidas e seus metabólitos são eliminados pelo rim. Pacientes com insuficiência renal podem estar em maior risco de efeitos adversos de sulfonamidas devido à diminuição da droga folga. Além disso, sulfonamidas podem causar toxicidade renal secundária a crystalluria, incluindo uro - e nefrolitíase, nefrite, tóxicos nephrosis, hematúria, proteinúria e, elevados BUN e creatinina. Hidratação adequada e de débito urinário (> 1,5 L/dia) deve ser mantida durante a sulfonamida de administração. Testes de função Renal e exame de urina deve ser realizado regularmente durante terapia prolongada (> 2 semanas). Alguns fabricantes tópica de sulfonamida produtos não recomendamos seu uso em pacientes com comprometimento da função renal.

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