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Brimonidine and brinzolamide ophthalmic e Doença hepática

Resultado da verificação da interação do medicamento Brimonidine and brinzolamide ophthalmic com doença Doença hepática quanto a segurança no uso em conjunto.

Resultado da verificação:

Brimonidine and brinzolamide ophthalmic <> Doença hepática

Relevância: 23.07.2019 Revisor: Shkutko P.M., M.D., in

Na verificação da interação, conforme informações das fontes confiáveis como Drugs.com, Rxlist.com, Webmd.com, Medscape.com, foram identificadas as contra-indicações ou efeitos colaterais que podem prejudicar a saúde ou aumentar efeito negativo ao consumir o medicamento com esta doença concomitante.

Consumidor:

Sulfonamidas pode ser absorvido sistemicamente, quando aplicado à pele, olhos ou membranas mucosas. Hepatotoxicidade, incluindo icterícia, difuso necrose hepatocelular, hipersensibilidade, hepatite e insuficiência hepática, raramente tem sido relatada em pacientes recebendo sulfonamidas. Além disso, sulfonamidas são parcialmente metabolizado pelo fígado e pode se acumular em pacientes com insuficiência hepática. A terapia tópica com sulfonamidas deve ser administrado com cautela em pacientes com doença hepática.

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