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Abacavir, dolutegravir, and lamivudine e Pancreatite

Resultado da verificação da interação do medicamento Abacavir, dolutegravir, and lamivudine com doença Pancreatite quanto a segurança no uso em conjunto.

Resultado da verificação:

Abacavir, dolutegravir, and lamivudine <> Pancreatite

Relevância: 23.07.2019 Revisor: Shkutko P.M., M.D., in

Na verificação da interação, conforme informações das fontes confiáveis como Drugs.com, Rxlist.com, Webmd.com, Medscape.com, foram identificadas as contra-indicações ou efeitos colaterais que podem prejudicar a saúde ou aumentar efeito negativo ao consumir o medicamento com esta doença concomitante.

Consumidor:

Os inibidores da transcriptase reversa, a didanosina (ddI), zalcitabina (ddC), estavudina (d4T) e lamivudina (3TC), pode causar pancreatite. A incidência é geralmente baixa, mas é de aproximadamente 7% com ddI, e até 15% em pacientes pediátricos dado 3TC. Pacientes com história ou fatores de risco conhecidos para a pancreatite, tais como o abuso de álcool ou hipertrigliceridemia, devem ser cuidadosamente monitorizados durante o tratamento com estes agentes. O tratamento deve ser interrompido aos primeiros sinais ou sintomas sugestivos de pancreatite (por exemplo, náuseas, vômitos, dor abdominal, hyperamylasemia com dysglycemia, aumento de triglicérides, diminuindo séricos de cálcio), e, de preferência, permanentemente descontinuado caso clínico de pancreatite desenvolve.

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