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Pediazole e Doença hepática

Resultado da verificação da interação do medicamento Pediazole com doença Doença hepática quanto a segurança no uso em conjunto.

Resultado da verificação:
Pediazole <> Doença hepática
Relevância: 23.07.2019 Revisor: Shkutko P.M., M.D., in

Na verificação da interação, conforme informações das fontes confiáveis como Drugs.com, Rxlist.com, Webmd.com, Medscape.com, foram identificadas as contra-indicações ou efeitos colaterais que podem prejudicar a saúde ou aumentar efeito negativo ao consumir o medicamento com esta doença concomitante.

Consumidor:

O uso de eritromicina oral, especialmente erythromycin estolate e erythromycin ethylsuccinate, tem sido associado com ocasionais casos de disfunção hepática, incluindo aumento das enzimas hepáticas e hepatocelular e/ou hepatite colestática. O tratamento com eritromicina oral deve ser administrado com cautela em pacientes com doença hepática. Além disso, a eritromicina é principalmente excretada pelo fígado na bile. O efeito do fígado e/ou biliar doença em eritromicina folga é desconhecido. Empírico de ajustes de dose podem ser apropriada em pacientes com insuficiência hepática ou biliar função.

Referências
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Pediazole

Nome genérico: erythromycin / sulfisoxazole

Marca comercial:

Sinônimos: Pediazole (Oral)

Pediazole <> Doença hepática
Relevância: 23.07.2019 Revisor: Shkutko P.M., M.D., in

Na verificação da interação, conforme informações das fontes confiáveis como Drugs.com, Rxlist.com, Webmd.com, Medscape.com, foram identificadas as contra-indicações ou efeitos colaterais que podem prejudicar a saúde ou aumentar efeito negativo ao consumir o medicamento com esta doença concomitante.

Consumidor:

Hepatotoxicidade, incluindo icterícia, difuso necrose hepatocelular, hipersensibilidade, hepatite e insuficiência hepática, raramente tem sido relatada em pacientes recebendo sulfonamidas. Além disso, sulfonamidas são parcialmente metabolizado pelo fígado e pode se acumular em pacientes com insuficiência hepática. O tratamento com sulfonamidas deve ser administrado com cautela em pacientes com doença hepática.

Referências
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Pediazole

Nome genérico: erythromycin / sulfisoxazole

Marca comercial:

Sinônimos: Pediazole (Oral)

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