Pesquisa de medicamentos por nome

Paliperidone e NMS

Resultado da verificação da interação do medicamento Paliperidone com doença NMS quanto a segurança no uso em conjunto.

Resultado da verificação:

Paliperidone <> NMS

Relevância: 23.07.2019 Revisor: Shkutko P.M., M.D., in

Na verificação da interação, conforme informações das fontes confiáveis como Drugs.com, Rxlist.com, Webmd.com, Medscape.com, foram identificadas as contra-indicações ou efeitos colaterais que podem prejudicar a saúde ou aumentar efeito negativo ao consumir o medicamento com esta doença concomitante.

Consumidor:

A central de bloqueio dopaminérgico efeitos dos neurolépticos, pode precipitar ou agravar um potencialmente fatal sintoma complexo conhecido como síndrome maligna dos neurolépticos (SMN). NMS é observada com mais freqüência quando a alta potência de agentes como o haloperidol são administradas por via intramuscular, mas pode ocorrer com qualquer dos neurolépticos agente determinado por qualquer período de tempo. Manifestações clínicas do SMN incluem a hiperpirexia, rigidez muscular, estado mental alterado e instabilidade autonômica (pulso irregular ou a pressão arterial, taquicardia, diaphoresis e arritmias cardíacas). Sinais adicionais podem incluir elevados de creatinafosfoquinase, myoglobinuria, e insuficiência renal aguda. Neurolépticos, não deve ser administrado a pacientes com o NANÔMETROS e deve ser imediatamente interrompido se actualmente a ser administrado em tais pacientes. Em pacientes com uma história de SMN, introdução ou reintrodução de neurolépticos deve ser cuidadosamente considerado, já que o NMS pode se repetir.

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